Physician Support  |  Contact Us

HOME LEARN MORE STUDIES NEWS SOFTWARE PURCHASE Call Us at 1-800-766-0884 Pain Generator Detection Sensitivity and Specificity in Detecting Pre-DRG Pathology Evidence Based Medicine The patented modulated Axon-II signal is designed to isolate specific types of sensory fibers. This is especially valuable in helping detect dysfunction in the A-delta fibers for evaluation of possible pre-DRG pathway pathology. Verification of firing is supported by the well documented fact that A-delta fibers are literally "hardwired" to the ventral motor pathway, so when they fire they not only produce a detectable action potential but additonally cause a subthreshold potential in the associated ventral motor pathway. Axon-II alone, or in conjunction with the potentiometer, can in a few minutes assess all the major nerve in a region to help detect the one or two requiring the highest voltage amplitude to initiate firing. Most important, the patient is his own control independent of age, gender or population data. As documented in medical text, conventional EMG/NCV cannot access the pain generating fibers of the pre-DRG in the absence of gross motor deficit, which is fairly rare, since most neck and back pain patient do not complain of, or demonstrate, weakness. The Fallacy of Spontaneous Recovery Based on the studies by Donelson et al. The Low Back Pain Experience: Natural History Survey - North American McKenzie Conf. Orando FL (2000) and Wayman et al. A Prospective Follow-Up Study of Low Back Pain in the Community - Spine 2000 that Though 40 - 50% of low back pain cases spontaneously recover within two weeks and 80 - 90% have recovered by two months, 60 - 90% suffer recurrences with progressively worsening, increased disability, longer duration and increasing peripheral radiation. It would seem logical that the key is accurate diagnosis of the level and side of nerve root lesion so appropriate intervention can prevent recurrences and increasing disability. The Axon-II can be a valuable tool in this regard. Fibromyalgia The Axon-II has been shown to detect pre-DRG pathology in most of these patients and has been reported to allow successful treatment in many such cases. Double Objective Proof Preliminary findings support that pre-DRG pathology may have a close correlation with abnormal vertebral motion as viewed on A-P lateral bending x-ray. It is suspected that diminished proprioceptive sensory input can affect spinal motor function, which is well documented in Guyton & Hall, and other medical physiology textbooks, that the small intrinsic muscles of the spine are under major controlled on a level by level in the spinal cord. See Guyton & Hall 9th Edition Page 705 SPECIFICATIONS Control is a custom ASIS digital logic controller Dimensions: System consists of the base unit (stimulus and response) mounted on a cart with a computer and printer. The system stands 3' to 4' high, approximately 2.5' wide and 1' to 1.5' deep. The base unit is 12.5 wide, 12" deep, and 5" high and weights 11.5 lbs. Operation requires both hands to manipulate the controls. Not a handheld device. Two LCD Displays: Stimulus Output 1" X 2", Response Potentiometer 1" x 4" Three Outputs: 5 Hz, 250 Hz and 2000 Hz each with waveforms and modulations covered by foreign and U.S. patents. Output Maximum: 9.99 mA / 50 Volts. Resolution Measurement: Non-Stepped Gradient. Device Features: Audible Function Changes, Power On, Test Modality, Automatic Calibration, Auto Low Power Warning/Flashing Red Light, Auto Power-up at 250 Hz frequency setting. Two Electrodes: One single large common ground 4" X 4", second gold tip electrode with disposable fiber saline impregnated. Potentiometer: Conductive plastic with less than 1% dynamic noise measuring total amplitude of millivoltage and combined action potential and sub-threshold potential. Response graphic display and computer printed hardcopy capable. United States Clearances: FDA Class II device. Prototype granted Safe & Effective FDA marketing clearance December 1, 1997. European Union Class - I with CE mark.

Sole Distributor and Manufacturer:  PainDx, Inc. - Axon-IITM NCSs SystemTM PHONE: 1-800-766-0884  -  E-MAIL: email@nervepathology.com Home  |  Learn More  |  Studies  |  News  |  Software  |  Warnings  |  Physician Support  |  Contact Us  |  Purchase This website is not for general public use. It is meant for physician reference only. Nothing presented is meant to represent or imply use other than the FDA Indication and usage. FDA Indications and Usage: The Axon-IITM NCSs is a diagnostic device that allows the quantitative detection of various sensory neurological impairments caused by various pathological conditions or toxic substance exposures. The subject population for whom this device can be used for diagnostic purposes includes any individual capable of communicating the perception of cutaneous sensation (with the potentiometer, which has a separate FDA clearance, the test is not dependent on the subject reporting perception of the cutaneous sensation, since the action potential of the nerve firing is detectable by the potentiometer). The Axon-IITM NCSs diagnostic examination may be conducted as part the neurological examination or for screening to detect peripheral neuropathies. Legal Notice DOCUMENTS PainDx, Incorporated. gives permission to use documents on this web site provided that: The PainDx, Inc. copyright appears in copies and a permission notice appear, © 2010 PainDx, Inc. Documents from this site are for informational and non-commercial or personal use only. Such will not be copied or posted to any network computer or broadcast or published in any media or method now or hereafter developed, and No modification of any document is made and no unauthorized purpose is prohibited by law. Violation may result in civil and/or criminal penalties. Materials do not use the design or layout of the website. INFORMATION ON PAINDX, INCORPORATED'S WEBSITE INCLUDING SPECIFICATIONS, APPEARANCE AND APPLICABILITY MAY BE SUBJECT TO CHANGE WITHOUT NOTICE. NO REPRESENTATIONS ARE MADE OR IMPLIED AS TO THE SUITABILITY OF THE INFORMATION ON THIS SITE FOR ANY PURPOSE. THE FULL CONTENTS ARE PROVIDED "AS IS" WITHOUT WARRANTY OF ANY KIND AND ARE SUBJECT TO CHANGE WITHOUT NOTICE. ANY TYPE OF RISK WHICH MAY ARISE OUT OF USE OF THIS INFORMATION REMAINS WITH THE RECIPIENT. IN NO EVENT SHALL PAINDX, INCORPORATED BE LIABLE FOR ANY DIRECT, CONSEQUENTIAL, INCIDENTAL, SPECIAL, PUNITIVE OR OTHER DAMAGES (INCLUDING WITHOUT LIMITATION, DAMAGES FOR LOSS OF BUSINESS PROFITS, BUSINESS INTERRUPTION), EVEN IF PAINDX, INCORPORATED HAS BEEN ADVISED OF THE POSSIBILITY OF SUCH DAMAGES. TRADEMARK NOTICE All trademarks displayed on this website are subject to the U.S. trademark law, which support that any unauthorized use of trademarks is strictly prohibited. Copyright © 2010 PainDx, Inc. - Axon-IITM NCSs SystemTM  All Rights Reserved.